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April 24, 2025 10 min read

Everyone experiences emotional ups and downs, but for some, the intensity and unpredictability of these shifts—especially when linked to conditions like bipolar disorder or other mental health conditions—can become disruptive. Mood stabilizers, whether prescribed or natural, are often used to support emotional balance in individuals experiencing daily stress or mild mood fluctuations. Clinical symptoms like mania or severe depression should be managed with professional medical care.1

People taking mood stabilizers often want to know what to expect—how do mood stabilizers make you feel, how long do mood changes last, and are mood stabilizers addictive? Understanding the effects of mood-stabilizing medication, including natural options, can help individuals make informed choices about their mental health and care.

This article explores how mood stabilizers work, how they may help reduce mood swings, what common side effects may occur, and how natural remedies like omega-3s, saffron, and Rhodiola rosea may offer emotional balance for those managing mood disorder symptoms or other mental illnesses.

What Are Mood Stabilizers, and What Are They Used For?

Image of a brain scan.

Mood stabilizers are used to treat symptoms related to mood disorders, such as bipolar disorder, schizoaffective disorder, and other mental health conditions that involve strong mood swings. These medications or natural supplements help reduce the intensity of emotional highs, like mania, and lows, such as depressive episodes.2

Prescription mood stabilizers are believed to support more balanced brain activity. Natural options may influence mood-related processes in more subtle ways, which helps create a more balanced and steady emotional state. People often take mood-stabilizing medication to manage manic and depressive episodes, reduce mood swings, and prevent future emotional episodes from becoming severe.

While they are often used to treat bipolar disorder, they may also be used to support people with other mental disorders that involve mood swings linked to stress, impulsivity, or emotional instability.

What’s the Difference Between Prescription and Natural Options?

Prescription mood stabilizers—such as lithium carbonate, valproic acid, and lamotrigine—are often used to treat bipolar disorder, treat epilepsy, and manage severe symptoms of mood disorders under a doctor’s care. These medications may require regular blood tests, monitoring of blood levels, and adjustments to the starting dose. They can be paired with other medications, like antipsychotic medications or antidepressants, depending on the diagnosis.

Natural options, including herbal remedies like saffron, Rhodiola rosea, and omega-3 fatty acids, do not require a prescription and are typically used to support emotional wellness in daily life. While they don’t treat mania or severe depressive episodes, they have been studied for their potential to support emotional wellness and mental clarity during periods of stress for people dealing with mild mood swings or stress-related symptoms.

How Do Natural Mood Stabilizers Make You Feel?

Natural mood stabilizers are often chosen for their gentle support and lower risk of strong side effects. They are not used to treat episodes of mania or severe depression, but they can help support emotional stability in people experiencing daily stress or low mood.

A Sense of Calm Without Feeling Sedated

Many people who take natural mood stabilizers report feeling more at ease and less overwhelmed without the tiredness or drowsiness that can come from some prescription options. Instead of feeling sedated, users often notice less racing thoughts, reduced irritability, and fewer emotional ups and downs. Unlike prescription drugs that may cause blurred vision, dry mouth, or difficulty concentrating in the first few weeks, natural options usually support calmness while helping people stay alert and engaged.

More Emotional Stability Throughout the Day

One of the most noticeable effects of mood support from natural remedies is feeling more balanced throughout the day. People often describe themselves as less reactive to stress and better able to manage their emotions without feeling numb.

These changes help reduce mood swings and support a more even emotional response to daily challenges. While not everyone experiences the same results, this steadying effect may help those with mood swings linked to stress, hormonal shifts, or other mental health conditions feel more in control.

Clearer Thinking and Better Focus

Some natural mood stabilizers also help with mental clarity. Ingredients like omega-3 fatty acids and Rhodiola rosea have been studied for their ability to support cognitive function and emotional well-being. Users sometimes report feeling more present, having sharper focus, and thinking more clearly, which can improve daily performance at work or home. These natural options are generally well-tolerated, though individual reactions and interactions with other medications are still possible and may be easier to tolerate during long-term treatment.

Gradual and Gentle Effects, Not Instant Changes

Person pouring a cup of tea.

Natural mood stabilizers usually do not produce immediate changes. The body adjusts slowly, and effects tend to build up over time. Most people notice benefits after a few days to a few weeks of regular use rather than after a single dose.

This slower pace is one reason these remedies are used to support wellness rather than to treat severe mental illnesses. The gentle nature of these supports may appeal to people looking for fewer common side effects like flu-like symptoms, joint pain, or sudden rash, which can sometimes appear with prescription medications.

Ingredients That Naturally Support a Balanced Mood

Some natural ingredients have been studied for their calming and mood-stabilizing effects. These can support emotional balance without the more potent side effects linked to prescription mood-stabilizing medication.

Saffron Extract

Saffron extract has been clinically shown to promote emotional balance and support a positive mood. Studies suggest it may help reduce low mood and improve people's response to daily stressors. In healthy adults, some preliminary studies indicate that saffron extract may help support mood in individuals with subclinical symptoms of stress or sadness and emotional discomfort. When taken consistently, it may also help reduce sleep problems and improve overall well-being. Because it is not used to treat bipolar disorder or acute mania, saffron is better suited for mild mood symptoms and daily emotional support.5

L-Theanine

L-Theanine is an amino acid found in green tea. It helps increase calming brainwaves called alpha waves, which are linked to relaxed alertness. People often take L-theanine to reduce feelings of tension without becoming sleepy. Unlike other medications that may cause drowsiness, dry mouth, or slurred speech, L-theanine has been studied for its potential to support a relaxed yet alert mental state. It’s often included in natural remedies used to treat symptoms of stress and support overall mental health.

Rhodiola Rosea

Rhodiola rosea is an adaptogenic herb known to support stress resilience and improve feelings of energy. It has been used to reduce mental fatigue, support focus, and help with mood swings linked to stress. Clinical studies show that Rhodiola may help people feel more emotionally steady throughout the day, especially during challenging periods. While it does not replace medication used to treat bipolar disorder or schizoaffective disorder, it can be part of a broader support plan for mental health.4

Magnesium

Magnesium plays a key role in regulating neurotransmitters that influence mood and stress. Low magnesium levels have been linked to mood disorder symptoms like anxiety, irritability, and sleep problems. Supplementing with magnesium plays a role in brain function and may contribute to a sense of calm and emotional steadiness, especially when included as part of a healthy die. It’s often recommended alongside a balanced diet and may be combined with other medications under a doctor’s supervision for people managing mental disorders.

Omega-3 Fatty Acids

Saffron and yellow capsules.

Omega-3 fatty acids in fish oil and plant-based sources support brain structure and long-term emotional health. Some studies suggest that omega-3 fatty acids may support mood and enhance the effects of prescribed antidepressants in certain individuals. They support healthy brain cell function and may help reduce symptoms of low mood in some people. Omega-3s are not used to treat mania or severe mental illnesses but may help manage mild to moderate mood symptoms when taken as part of a long-term treatment plan.6

What Can Influence How You Feel on a Mood Stabilizer?

How you feel when taking mood stabilizers—natural or prescription—can depend on several factors. These include how often you take them, your daily habits, and how your brain responds to different types of mood support.3

Consistency of Use

Taking mood stabilizers or natural remedies consistently is essential for the best results. The body adjusts gradually when these supports are used regularly, leading to more stable effects. Regular use may be needed for consistent results, and stopping abruptly may reduce their perceived effectiveness or limit the benefits. People often ask how long mood changes take on stabilizers; natural options usually take several days to a few weeks of steady use to feel noticeable results.

Lifestyle and Diet

Daily routines play a significant role in how mood stabilizers work. Sleep, physical activity, and nutrition can all affect emotional health. Supporting your body with healthy habits helps enhance the effects of mood stabilizers and herbal remedies.

Helpful daily habits include:

  • Getting 7–9 hours of sleep each night

  • Avoiding street drugs and excess alcohol

  • Eating a balanced diet rich in folic acid, magnesium, and omega-3s

  • Exercising regularly to release mood-supporting chemicals

  • Staying hydrated to prevent brain fog and low-energy

  • Managing screen time to reduce sleep problems

Your Unique Brain Chemistry

Not everyone responds to mood stabilizers the same way. Some may feel better after a short time, while others may need more time to find the right product or dose. Factors like age, genetics, and other mental health conditions can affect how the body reacts.

Prescription medications like lithium citrate or valproic acid often require regular blood tests to check blood levels and adjust the starting dose. The process is usually gentler with natural options, but finding the proper routine may take time. Working with a healthcare provider can help if symptoms like sudden pain, itchy skin, or joint pain appear.

What to Expect in the First Few Days or Weeks

Starting a natural mood stabilizer can lead to small but essential changes in how you feel and react emotionally. These changes may be gradual, especially during the early stages.

Subtle Shifts in Emotional Reactivity

Many people report feeling less emotionally reactive during the first few weeks of taking natural mood stabilizers. You may notice you’re not as easily irritated or overwhelmed by daily stress. This shift doesn’t mean your feelings disappear—it means your responses may feel more controlled and less intense. For those with mood swings linked to stress or low mood, these early changes can be encouraging signs that the support is working.

Improved Sleep or Reduced Tension

Some natural ingredients used to treat symptoms of emotional imbalance, like magnesium or L-theanine, can help calm the mind and body. As tension decreases, falling asleep may become easier, and sleep problems may lessen. While not everyone experiences the same effects, this calming support can help the body adjust more smoothly, especially when transitioning into a new mood support routine.

Feeling More “Like Yourself”

A split image showing a woman looking overwhelmed on one side and emotionally calm and focused on the other.

A common goal when taking mood stabilizers is to feel emotionally steady without feeling dull or disconnected. Natural supports are designed to help you feel more like yourself—clear-headed, calm, and able to manage everyday life with more ease. Unlike medications that may cause blurred vision or slurred speech in some people, natural remedies aim to promote stability without strong side effects or emotional flatness.

Are Natural Mood Stabilizers Safe?

Peaceful nature-inspired scene showing a person on a path.

Most natural mood stabilizers are well-tolerated and not linked to common side effects like sudden rash, dry mouth, or involuntary movements often seen with certain prescription medications. These ingredients are frequently used to support emotional balance in the general population, including those who are not taking medication for mental disorders.7

Still, it’s important to talk to a healthcare provider before adding new supplements, especially if you are already taking medication to treat depression, treat mania, or manage other mental health conditions. Combining natural supports with other medications should always be guided by a professional to avoid unwanted interactions or changes in blood levels.

Support Calm and Clarity—Naturally

Natural mood stabilizers offer a steady, effective way to support emotional balance without causing the strong side effects that sometimes come with prescription medications. These supplements may promote mental clarity and a more even emotional state when combined with supportive lifestyle habits and make daily stress feel more manageable. When taken regularly and paired with supportive habits like a balanced diet and proper sleep, these remedies may help you feel more centered and calm—bringing greater ease to handling life's emotional ups and downs.

Frequently Asked Questions

How do natural mood stabilizers make you feel?

They help you feel more emotionally balanced, calm, and focused without feeling sedated or numb.

Can mood stabilizers help with daily stress?

Natural mood stabilizers are used to reduce mood swings linked to stress and support a steady emotional state.

Will I feel “different” or “numb” after taking a mood stabilizer?

Natural mood stabilizers are designed to help you feel more like yourself—not emotionally flat or disconnected.

How long do natural mood stabilizers take to work?

You may notice subtle improvements within the first few weeks as your body adjusts gradually.

Are natural mood stabilizers safe to take long-term?

Most are safe for long-term treatment, but it’s best to consult a doctor immediately if it is combined with other medications.


References

  1. Chen, C. K., Yang, S. Y., Park, S. C., Jang, O. J., Zhu, X., Xiang, Y. T., Ouyang, W. C., Javed, A., Khan, M. N. S., Grover, S., Avasthi, A., Kallivayalil, R. A., Chee, K. Y., Chemi, N., Kato, T. A., Hayakawa, K., Pariwatcharakul, P., Maramis, M., Seneviratne, L., Sim, K., … Lin, S. K. (2023). Clinical use of mood stabilizers beyond treatment for bipolar disorder: The REAP-MS study. Asian journal of psychiatry, 85, 103613. https://doi.org/10.1016/j.ajp.2023.103613

  2. Gould, T. D., Chen, G., & Manji, H. K. (2002). Mood stabilizer psychopharmacology. Clinical neuroscience research, 2(3-4), 193–212. https://doi.org/10.1016/S1566-2772(02)00044-0

  3. Harwood A. J. (2003). Neurodevelopment and mood stabilizers. Current molecular medicine, 3(5), 472–482. https://doi.org/10.2174/1566524033479672

  4. Ivanova Stojcheva, E., & Quintela, J. C. (2022). The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence. Molecules (Basel, Switzerland), 27(12), 3902. https://doi.org/10.3390/molecules27123902

  5. Jackson, P. A., Forster, J., Khan, J., Pouchieu, C., Dubreuil, S., Gaudout, D., Moras, B., Pourtau, L., Joffre, F., Vaysse, C., Bertrand, K., Abrous, H., Vauzour, D., Brossaud, J., Corcuff, J. B., Capuron, L., & Kennedy, D. O. (2021). Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial. Frontiers in nutrition, 7, 606124. https://doi.org/10.3389/fnut.2020.606124

  6. Mehdi, S., Manohar, K., Shariff, A., Kinattingal, N., Wani, S. U. D., Alshehri, S., Imam, M. T., Shakeel, F., & Krishna, K. L. (2023). Omega-3 Fatty Acids Supplementation in the Treatment of Depression: An Observational Study. Journal of personalized medicine, 13(2), 224. https://doi.org/10.3390/jpm13020224

  7. Simonetti, A., Koukopoulos, A. E., Kotzalidis, G. D., Janiri, D., De Chiara, L., Janiri, L., & Sani, G. (2020). Stabilization Beyond Mood: Stabilizing Patients With Bipolar Disorder in the Various Phases of Life. Frontiers in psychiatry, 11, 247. https://doi.org/10.3389/fpsyt.2020.00247


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